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Activation of Psychosis and or Mania: Antidepressants can precipitate manic episodes in bipolar disorder patients during the depressed phase of their illness and may activate latent psychosis in other susceptible patients. Events are bupropion precio further categorized by body system and listed in order of decreasing frequency according to the following definitions of frequency: Frequent adverse events are defined as those occurring in at least 100 patients. Administration of Bupropion Hydrochloride Extended-Release Tablets, USP SR to patients receiving either levodopa or amantadine concurrently should be undertaken with caution, using small initial doses and gradual dose increases. In one study, there was no difference between bupropion and other antidepressants in the occurrence of birth defects. To learn which drugs and herbs are or can be ototoxic, see Drugs Exposed Do not give this medication to anyone younger than 18 years old without the advice of doctor.